For quite a while now I’ve been using a TC Electronics Plethora X5 - five “slots” into which you can put any of the TC Tone print pedals. Each set of five constitutes a “board” and the unit can hold 127 boards! There are plenty of videos showing how it can be used, but I tend to have a relatively simple setup, with the effects being mainly modulation/delay/reverb in the effects loop of the amp. No overdrives, but I use the amp’s overdrive for solos and a Fuchs Plush Drive in front of the amp for a bit of crunch.
My setup is Guitar -> wah -> Plush Drive -> Plethora input -> Plethora Insert send to amp input -> amp fx send to Plethora Insert return -> plethora output to amp fx return. The board I tend to use most has the Viscous Vibe as the first pedal, before the Insert Send (so the signal is going from the vibe into the amp’s input), with the signal from the amp’s fx send into Corona Chorus, Pipeline Tremolo, Flashback Delay and Hall of Fame Reverb, and back to the amp’s fx return. I hope that makes sense...
You can edit the effects on the unit, and you don’t have to press anything to save - your changes are saved when you exit edit mode. There are firmware updates, most recently the Infinity Sample Sustainer has been added to the available toneprints.
Ever since I heard the 1973 Robert Fripp/Brian Eno collaboration No Pussyfooting, I’ve been a fan of ambient music. They used a couple of Revoxes for tape delays, but this chap shows how you can do it with the Plethora...