yeah Rich's post already mentioned that along with the wider headstock, push/pull tone pots, and the weight relief. Personally I am not a fan of any weight relief.
I like my standard H150s, especially because I modded them with all the electronic and hardware choices that I like, and the one that I bought used was cheap, I got it for right around a grand! Even with the pickups and hardware changes it came in under $1600. My new one I paid around $2300 for and still had to upgrade. Which is still cheaper than a Custom Core these days:) I also had to recuit the nut and dress frets on the H150s. And both of them are considerably heavier than the lighter Custom Cores. I also like the aesthetic touches of the Custom Cores better, especially the bigger headstock, the slightly different lower horn, and the body carve, which I love the look of. That said, I don't like the custom core tuner choices, or the hardware. And most likely I would replace the pickups as I'm not a fan of potted pickups. That's why I don't own one. If I didn't have to upgrade, I would buy a used one.